Abstract: In order to solve the problems of organic solvent volatilization, environmental pollution and human health hazards in the production of synthetic leather, waterborne polyurethane was used to realize the clean production of synthetic leather products. The production process and key technical parameters of waterborne polyurethane film formation in the coating layer of dry process line of synthetic leather products were studied. The key technical parameters of film formation mechanism, slurry viscosity, roll coating gap, production speed, drying temperature and optimal amount of additives (i.e., wetting agent and thickener) were obtained. The best film forming effect of waterborne polyurethane on dry coating was achieved, It provides a reference for the production and application of waterborne polyurethane in dry coating of synthetic leather.