Abstract: The main risk factors and intervention measures of occupational lower extremity musculoskeletal disorders were studied to provide theoretical basis for preventing and alleviating domestic occupational lower extremity musculoskeletal disorders. By summarizing and analyzing the existing literature, this paper evaluates the influencing factors of occupational lower extremity musculoskeletal disorders, and discusses the effect of intervention measures in reducing the occurrence of such disorders and relieving symptoms. The conclusion shows that occupational musculoskeletal disorders are closely related to individual characteristics, occupational nature and social psychological factors, and effective intervention measures, including exercise, reasonable work and rest, and functional assistive devices, can effectively prevent and alleviate the symptoms of lower limb musculoskeletal disorders.